Trang: 16
Tập 33, số 8 2023
The neutralization antibodies of SARS-CoV-2 during COVID-19 outbreak in Da Nang, Vietnam, July - August 2020
Tác giả: Le Thi Thanh, Hoang Vu Mai Phuong, Nguyen Le Khanh Hang, Vuong Duc Cuong, Nguyen
Phuong Anh, Ung Thi Hong Trang, Tran Thi Thu Huong, Nguyen Vu Son, Le Thi Quynh Mai
Tóm tắt:
Beside molecular tests (realtime RT-PCR) which known as the golden key for SARS-CoV-2 confirmation, antibody
test can be used to determine the responses in human antibody to SARS-CoV-2 and the result of plaque reduction
neutralization test (PRNT) could identify the people who have been exposed with the SARS-CoV-2 and carried the
neutralization antibody. Total 9936 samples were collected in 3 groups healthcare workers, inpatients (not related to
COVID-19 before) and community in Da Nang city during July-August 2020. These cross sectional results showed
that the rate of neutralization antibody in three groups in this research was 0.2%, in that, 0.1% in community, 0.2%
in inpatient and 0.4% in healthcare workers. Follow-up study with 1253 paired sera of healthcare workers, the rate
of SARS-CoV-2 neutralization antibody was determined as 2.1%. A downward trend of this neutralization antibody
overtime has been shown in the study.
Summary:
Từ khóa:
Seroprevalence; SARS-CoV-2; neutralizing antibodies; Da Nang
DOI: https://doi.org/10.51403/0868-2836/2023/1473
File nội dung:
o230816.pdf
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